[Bioperl-l] Tool to mutate DNA sequence

Torsten Seemann torsten.seemann at infotech.monash.edu.au
Thu Feb 9 06:15:28 EST 2006


Ryan,

> Does anyone know of tool to mutate a DNA sequence by a specified amount?
> For instance, say I have a DNA sequence 1000 bases long, and I want to
> simulate mutations to make it 75% (or 80%, etc) similar to the original.

The EMBOSS suite comes with a tool called "msbar" which can controllably 
mutate sequences:

http://emboss.sourceforge.net/apps/msbar.html

-- 
Torsten Seemann
Victorian Bioinformatics Consortium, Monash University, Australia
http://www.vicbioinformatics.com/


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