[Bioperl-l] Tool to mutate DNA sequence

Jason Stajich jason.stajich at duke.edu
Thu Feb 9 14:10:54 EST 2006


Depending on whether or not you want to use evolutionary realistic  
models...
* evolver which comes with PAML lets you evolve sequences on a tree
* SeqGen from Andrew Rambaut http://evolve.zoo.ox.ac.uk/software.html? 
id=seqgen
also lets you do this
I believe there are PISE interfaces to both of these at the pasteur  
bioweb site - http://bioweb.pasteur.fr/

-jason
On Feb 8, 2006, at 11:46 PM, Ryan Golhar wrote:

> Does anyone know of tool to mutate a DNA sequence by a specified  
> amount?
> For instance, say I have a DNA sequence 1000 bases long, and I want to
> simulate mutations to make it 75% (or 80%, etc) similar to the  
> original.
>
>
> Ryan
>
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--
Jason Stajich
Duke University
http://www.duke.edu/~jes12




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