[Bioperl-l] Course: Computational and Comparative Genomics

William R. Pearson wrp at virginia.edu
Mon Jul 2 16:08:04 EDT 2007

Course announcement - Application deadline, July 15, 2007


Cold Spring Harbor
November 7 - 13, 200
Application Deadline: July 15, 2007


Pearson, William, Ph.D., University of Virginia, Charlottesville, VA
Smith, Randall, Ph.D., SmithKline Beecham Pharmaceuticals, King of
Prussia, PA

Beyond BLAST and FASTA - Alignment: from proteins to genomes - This
course presents a comprehensive overview of the theory and practice of
computational methods for extracting the maximum amount of information
from protein and DNA sequence similarity through sequence database
searches, statistical analysis, and multiple sequence alignment, and
genome scale alignment. Additional topics include gene finding,
dentifying signals in unaligned sequences, integration of genetic and
sequence information in biological databases.

The course combines lectures with hands-on exercises; students are
encouraged to pose challenging sequence analysis problems using their
own data. The course makes extensive use of local WWW pages to present
problem sets and the computing tools to solve them. Students use
Windows and Mac workstations attached to a UNIX server.

The course is designed for biologists seeking advanced training in
biological sequence analysis, computational biology core resource
directors and staff, and for scientists in other disciplines, such as
computer science, who wish to survey current research problems in
biological sequence analysis and comparative genomics.

The primary focus of the Computational and Comparative Genomics Course
is the theory and practice of algorithms used in computational
biology, with the goal of using current methods more effectively and
developing new algorithms. Cold Spring Harbor also offers a
"Programming for Biology" course, which focuses more on software

For additional information and the lecture schedule and problem sets
for the 2006 course, see:



To apply to the course, fill out and send in the form at:



Bill Pearson

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