[Bioperl-l] Amino Acid sequence to nucleotides sequence

Peter Cock p.j.a.cock at googlemail.com
Mon Apr 16 16:32:20 EDT 2012


On Mon, Apr 16, 2012 at 9:08 PM, shalu sharma <sharmashalu.bio at gmail.com> wrote:
> Hi All,
>            Is there any way in Bioperl i can convert amino acid sequences
> to nucleotide sequences.
>
> Thanks
> Shalu

Probably - but there is more than one answer since the codon
tables are a many-to-one mapping. Are you hoping for one
possible nucleotide sequence, perhaps with IUPAC ambiguity
characters? Perhaps a specific example of what you want
would help - back-translation is a fuzzy term.

If you are trying to combine a protein alignment with the
original unaligned nucleotide sequences to make a codon
alignment that's a different task.

Peter



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