Richard Mott's program to align cDNA and EST sequences to the genome using a splice-site aware algorithm. It is generally thought to be an accurate program but tends to be much slower than Sim4 or Exonerate.
References
- Mott R. EST_GENOME: a program to align spliced DNA sequences to unspliced genomic DNA. Comput Appl Biosci. 1997 Aug;13(4):477-8. PubMed ID:9283765 | HubMed [est2genome]